Diagnosis     

    
  

Asthma can be highly variable. It can be mild, moderate, or severe as shown in the table below. Asthma differs among people and over time. For example asthma can be moderate in childhood and mild in adulthood, and it can be severe only during certain seasons. The severity of asthma can be determined by assessment of symptoms and clinical signs. However, relying solely on these measures can be misleading, and use of PEFR measurements provides valuable additional information. Below the age of 5, the assessment and monitoring of severity with measurements of lung function, including PEFR, are not feasible. Lung functions can be measured with spirometer or peak flow meter.

Asthma therapy follows a stepwise approach in which the level of therapy is increased as the severity of asthma increases and therapy is decreased once control is achieved and sustained.

A doctor may ask following questions from the patient or the parents to establish diagnosis.

Does the patient have,

  • Recurrent attacks of wheezing?
  • Troublesome cough or wheeze at night or early in the morning?
  • Cough or wheeze after exercise?
  • Cough, wheeze, or chest tightness after exposure to airborne allergens or pollutants?
  • Colds that "go to the chest" or take more than 10 days to clear up?
  • Anti-asthma medicine? How frequently does the patient take it?

Classification of asthma severity depending on symptoms and lung functions:

Classification Clinical Features Before 
Treatment
Medication Required to maintain Control
Severe 
  • Multiple daily long term preventive medications:
    • high doses of inhaled corticosteroid.
    • long acting bronchodilator, and oral corticosteroid long term.
Moderate 
  • Symptoms > 1 time a week but < 1 time per day.
  • Exacerbations may affect activity and sleep.
  • Night time asthma symptoms > 2 times a month.
  • Daily use of inhaled short-acting  beta 2-agonist. 
  • PEF or FEV1 between 50% - 80% predicted/personal best peak flow.
  • Diurnal variability of PEF between 
    20% - 30%.
  • Daily long-term preventive medications: 
    • inhaled corticosteroid.
    • long-acting bronchodilator (especially for night time symptoms).
Mild
  • Exacerbations affect activity and sleep.
  • Night time Asthma symptoms < 1 time a week.
  • PEF or FEV1  > 80% predicted/personal best peak flow.
  • Diurnal variability of PEF < 20%.
  • One daily long-term preventive medication.
  • Possibly add a long-acting bronchodilator to anti-inflammatory medication (especially for night time symptoms).

* based on GINA guidelines

   



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