Company: Glaxo India Ltd.
Generic Drug: Salbutamol + Beclomethasone. Salbutamol (beta-adrenergic stimulant) is a bronchodilator while Beclomethasone (synthetic corticosteroid) has strong anti-inflammatory properties.
Indication: The combination therapy is recommended for treatment of asthma where requirement of inhaled bronchodilator and corticosteroid therapy in disease management is established.
Contraindication: Allergy or hypersensitivity to any component in the preparation.
Dosage and Administration:
For adult: Two inhalations, three to four times daily.
For children: One or two inhalations, two to four times daily.
*Ventoride inhaler can be used with the help of a device known as a spacer.
- It is indicated for routine management of asthma on long term basis. It is not to be use in acute attacks.
- Patients with cardiovascular risk need extra precaution while using it due to beta adrenergic effect of Salbutamol.
- Salbutamol can cause paradoxical brochospasm which should be treated instantly with some alternative drugs.
- Beclomethasone can cause systemic effects in high doses; these are Cushing’s syndrome, growth retardation in children, adrenal suppression, cataract and glaucoma.
- Patients with active pulmonary tuberculosis need special care while using it.
Side Effects/ Undesired effects/ Adverse drug reactions:
Salbutamol can cause following side effects: Mild tremor, headache, paradoxical bronchospasm, allergic reactions, hypokalemia, dizziness, tachycardia and muscle cramps. Beclomethasone dipropionate can cause following side effects: Oral candidiasis (thrush), hypersensitivity reactions, adrenal suppression, easy bruising of the skin, growth retardation in children, easy bruising of the skin, hoarseness and throat irritation.