Company: Glaxo India Ltd.

Generic Drug: Salbutamol + Beclomethasone. Salbutamol (beta-adrenergic stimulant) is a bronchodilator while Beclomethasone (synthetic corticosteroid) has strong anti-inflammatory properties.

Indication: The combination therapy is recommended for treatment of asthma where requirement of inhaled bronchodilator and corticosteroid therapy in disease management is established.

Contraindication: Allergy or hypersensitivity to any component in the preparation.

Dosage and Administration:

For adult: Two inhalations, three to four times daily.

For children: One or two inhalations, two to four times daily.

*Ventoride  inhaler can be used with the help of a device known as a spacer.

Special Precautions:

  • It is indicated for routine management of asthma on long term basis. It is not to be use in acute attacks.
  • Patients with cardiovascular risk need extra precaution while using it due to beta adrenergic effect of Salbutamol.
  • Salbutamol can cause paradoxical brochospasm which should be treated instantly with some alternative drugs.
  • Beclomethasone can cause systemic effects in high doses; these are Cushing’s syndrome, growth retardation in children, adrenal suppression, cataract and glaucoma.
  • Patients with active pulmonary tuberculosis need special care while using it.

Side Effects/ Undesired effects/ Adverse drug reactions:

Salbutamol can cause following side effects: Mild tremor, headache, paradoxical bronchospasm, allergic reactions, hypokalemia, dizziness, tachycardia and muscle cramps. Beclomethasone dipropionate can cause following side effects: Oral candidiasis (thrush), hypersensitivity reactions, adrenal suppression, easy bruising of the skin, growth retardation in children, easy bruising of the skin, hoarseness and throat irritation.

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